The subchondral bone is also known as your epiphysis. The subchondral plate is a layer of bone that separates your articular cartilage from the diaphysis. In the article on osteoarthritis, we saw research that the subchondral plate is capable of adapting by increasing in thickness(thereby increasing height). Previously I have written that you can increase in height by increasing the periosteal width of bones that have periosteum on the longitudinal ends of the bones. This is still true for bones like the flat bones of the skull. If you apply pressure to the bones of the skull you will grow taller.
However, some bones only have patches of periosteum and bones seem to have either articular cartilage or periosteum. We'd have to look at the histology of each and every bone to see where there's periosteum or not. But anyway, whether there's periosteum or not on the longitudinal ends of the vertabrae it's still possible to grow taller there. Periosteal progenitor cells are not the only way osteoblasts can be formed. Osteoblasts can be formed from the bone marrow in the epiphysis(these are called surface osteoblasts). These osteoblasts can deposit new bone on the subchondral plate. The only way this wouldn't be possible is under caloric restriction where all marrow turns to fat. This is why I think scientists believed that all marrow turned to fat after puberty. But no bone marrow remains and if the marrow does turn to fat this is easily reversible by consuming an appropriate amount of calories.
So you can grow taller by periosteal induced appositional growth in the flat bones of the skull. However, in other bones like the vertebrae you're growing by surface osteoblast deposition on the subchondral plate. Same method, LSJL increasing hydrostatic pressure and causing stem cell profileration and osteoblast differentiation just a slightly different mechanism.
Growth-related structural, biochemical, and mechanical properties of the functional bone-cartilage unit.
"Articular cartilage and subchondral bone act together, forming a unit as a weight-bearing loading-transmitting surface. [We] examine growth-related changes of cartilage mechanical properties and relate these changes to alterations in cartilage biochemical composition and subchondral bone structure. Tibiae and femora of both hindlimbs from 7- and 13-week-old female Sprague-Dawley rats were harvested. Immunohistochemical staining and protein expression analyses of collagen II, collagen IX, COMP and matrilin-3, histomorphometry of cartilage thickness and COMP staining height were performed. Growth decreased cartilage thickness, paralleled by a functional condensation of the underlying subchondral bone due to enchondral ossification. Cartilage mechanical properties seem to be rather influenced by growth-related changes in the assembly of major ECM proteins such as collagen II, collagen IX and matrilin-3 than by growth-related alterations in its underlying subchondral bone structure."
"COMP has been shown to influence the formation of collagen I and II fibrils by encouraging early association of collagen molecules and thereby accelerating fibrillogenesis, with a distinct organization of the fibrils"
"mice lacking collagen IX or matrilin-3 show osteoarthritis-like alterations"
"articular cartilage thickness decreases during growth. This reduction in cartilage thickness is caused by an advancement of the enchondral ossification front and the subsequent development of the subchondral bone"
"cartilage thickness correlates negatively with subchondral bone plate thickness and positively with subchondral bone plate porosity"
"The amount of matrilin-3 decreased (−19.4%) during growth"<-the upregulation of Matn3 by LSJL could be important to the length increase response.
Alterations of the subchondral bone in osteochondral repair--translational data and clinical evidence.
Alterations of the subchondral bone in osteochondral repair--translational data and clinical evidence.
"Efforts to unravel the complexity of subchondral bone alterations have identified (1) the upward migration of the subchondral bone plate, (2) the formation of intralesional osteophytes, (3) the appearance of subchondral bone cysts, and (4) the impairment of the osseous microarchitecture"
"Upward migration of the subchondral bone plate is defined as the expansion of the osteochondral junction above its original level with resulting elevation of the subchondral bone plate into the cartilaginous repair tissue"
"the level of the new subchondral bone plate gradually advances above its native position and the cartilaginous repair tissue degrades"
"Intralesional osteophytes are defined as focal, newly-formed bone located apical to the original cement line and projected into the cartilaginous repair tissue layer"
hey Tyler any update from lsjl?
ReplyDeleteYo Minigolfer, you need to come up with a way to stress the bones in the spine, so far I've come up with weighted landing and you've told me about shadow boxing, any other ways?
ReplyDeleteI do weighted landing and shadow boxing(more for hypoxia though but there have been some studies that have shown bone growth in the spine as a result of boxing). You can also press on each of the spinous process of each of your vertebrae. This is the best you can do in terms of LSJL but this increases hydrostatic pressure throughout the entire vertebrae. I'd like to do this but not enough time. You can also do farmer's walk, shield carry, refrigerator carry, from strongman.
ReplyDeletehow much can one grow with LSJL?
ReplyDelete